Cytokine gene polymorphisms and high-resolution-computed tomography score in idiopathic pulmonary fibrosis

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High-Resolution Computed Tomography in Idiopathic Pulmonary Fibrosis

Department of Radiology, and Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Health Sciences Center; National Jewish Medical and Research Center, Denver, Colorado; Department of Radiology, and Division of Pulmonary and Critical Care Medicine, University of Washington Medical Center, Seattle, Washington; Clinical Science and Biometrics Departments, InterMune, In...

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High-resolution computed tomography in idiopathic pulmonary fibrosis: diagnosis and prognosis.

RATIONALE High-resolution computed tomography (HRCT) is an integral aspect of the evaluation of patients with suspected idiopathic pulmonary fibrosis (IPF). However, few studies have evaluated its use in a large cohort. OBJECTIVES To describe HRCT features in patients with mild to moderate IPF, compare diagnostic evaluations by a radiology core (three thoracic radiologists) with those by stud...

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human multidrug resistance 1 gene polymorphisms and idiopathic pulmonary fibrosis

background: for the first time we tested an association between the human multidrug resistance gene 1 (mdr1) polymorphisms (snps) and idiopathic pulmonary fibrosis (ipf). several mdr1 polymorphisms are associated with pathologies in which they modify the drug susceptibility and pharmacokinetics. materials and methods: we genotyped three mdr1 polymorphisms of 48 ipf patients and 100 control subj...

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The Correlation of Brody High Resolution Computed Tomography Scoring System with Clinical Status and Pulmonary Function Test in Patients with Cystic Fibrosis

Background: To reduce the mortality and morbidity rates of cystic fibrosis (CF) patients, and to have an effective clinical management, it is important to monitor the progression of the disease. The aim of this study was to evaluate the progression of lung disease in CF patients by means of assessing the correlation of the CT scoring system with clinical status and pulmonary function test at th...

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Clinical Course and Changes in High-Resolution Computed Tomography Findings in Patients with Idiopathic Pulmonary Fibrosis without Honeycombing

Some patients with idiopathic pulmonary fibrosis (IPF) do not have honeycombing on high-resolution computed tomography (HRCT) at their initial evaluation. The clinical course and sequential changes in HRCT findings in these patients are not fully understood. We reviewed the cases of 43 patients with IPF without honeycombing on initial HRCT from institutions throughout Japan. All patients were d...

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ژورنال

عنوان ژورنال: Respiratory Medicine

سال: 2007

ISSN: 0954-6111

DOI: 10.1016/j.rmed.2006.09.013